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ea0016p175 | Diabetes and cardiovascular diseases | ECE2008

Long term N-acetylcysteine and L-arginine administration reduces endothelial activation and systolic blood pressure in hypertensive patients with type 2 diabetes mellitus

Masha Andi , Gigliardi Valentina Ramella , Brocato Loredana , Manzato Enzo , Berchio Arrigo , Massarenti Paola , Settanni Fabio , Bergamini Stefania , Iannone Anna , Martina Valentino

Objective: Reactive oxygen species and nitric oxide (NO) have recently been considered involved in the cardiovascular complications of patients with type 2 diabetes as NO is supposed to loose its physiological beneficial effects, due to the presence of oxygen radicals. For this reason, we tested the effects of L-arginine (ARG) and N-acetylcisteine (NAC) administration with the aim to increase NO physiological production reducing free radical formation.</p...

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Endocrine Abstracts

Long term N-acetylcysteine and L-arginine administration reduces endothelial activation and systolic blood pressure in hypertensive patients with type 2 diabetes mellitus

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